Profhilo is high-concentration hyaluronic acid: it hydrates deeply and improves skin quality immediately, but the effect lasts 6 to 9 months and it generates no structural collagen. Juvelook combines that hydrating component with PDLLA, which induces your own collagen over the following months, lasting 12 to 18 months. For dehydrated skin without loss of firmness, Profhilo is enough; once there is mild laxity, Juvelook adds what Profhilo cannot.
- Juvelook from
- Profhilo 6–9 months
- Juvelook 12–18 months
Reviewed by Dr. Oscar Barón · Cirujano plástico · SCCP
In summary: Profhilo and Juvelook both improve facial skin quality through injections but work through different mechanisms and address different needs: Profhilo uses ultra-high concentration hyaluronic acid (64mg/2ml) to produce deep bioremodeling hydration with immediate luminosity results lasting 6 months, requiring just 2 sessions; Juvelook combines PDLLA + non-cross-linked HA to stimulate structural collagen production progressively over 3–6 months with effects lasting 18–24 months in 2–3 sessions, and is the only option safe for the periocular area. Profhilo is the better choice for severe skin dryness and quick hydration results; Juvelook is the better choice when the goal is long-term collagen regeneration and treatment of the eye contour area.
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If you want to better understand how Juvelook works before deciding, read our article on what Juvelook is and how it acts on the skin.
Curious which treatment matches your skin’s hydration versus collagen needs? Schedule an assessment with our team.
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